Our work at the Yorkshire Laser Centre includes clinical trials of the effects of Photodynamic Therapy on different types of cancer. Some of the trials we have recently conducted include;
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PDT Clinical studies |
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Indication |
Title of study
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No’s of patients recruited. |
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Lung Cancer |
Study of the role of PDT in early central lung cancer: pilot study (K Moghissi YLC) |
30 |
|
Photodetection (for early lung cancer) |
A pilot study of the accuracy of fluorescence bronchoscopy versus white light bronchoscopy in the detection of early bronchogenic cancer in high-risk individuals (K Moghissi YLC) |
191 |
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Oesophageal Cancer |
Non-randomised comparison between endoscopic PDT and surgical resection in patients with early (stage I) oesophageal cancer (K Moghissi YLC) |
80 (40 for each arm) |
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Oesophageal Cancer |
Study to determine the place of endoscopic PDT within the range of treatment for oesophageal cancer. Matched pair subjects (K Moghissi YLC) |
280 out of 1343 patients
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Gynaecology |
Study of the role of PDT in VIN: single or multiple PDT cycle (non-randomised prospective) – (C Gan Consultant Gynaecologist NLAG NHS Trust/YLC) |
30 patients to date |
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Colo-rectal |
Pilot study of the role of PDT in AIN in patients with or without HIV (G Duthie Dept of Academic Surgery/YLC) |
26 |
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Urology |
Pilot study of the role of PDT in urothelial cancer ( L Coombs Consultant Urological Surgeon NLAG NHS Trust/YLC) |
6 patients to date |
